Hubrecht Imaging Center (HIC)


Hubrecht Imaging Center (HIC)
a.graaff@hubrecht.eu
Anko de Graaff
Hubrecht Institute
Uppsalalaan 8
3584 CT
Utrecht
hic
Anko de GraaffJacco van Rheenen
Widefield fluorescence microscopyConfocal microscopy

Multiphoton microscopy

Intravital imaging

Live cell imaging

FLIM

FRET

FRAP

Developmental Biology and Stem Cell Research
J Cell Sci. 2011 Feb 1;124(Pt 3):299-310.Intravital microscopy: new insights into metastasis of tumors.

Beerling E, Ritsma L, Vrisekoop N, Derksen PW, van Rheenen J.Cell. 2010 Oct 1;143(1):134-44.

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.

Snippert HJ, van der Flier LG, Sato T, van Es JH, van den Born M, Kroon-Veenboer C, Barker N, Klein AM, van Rheenen J, Simons BD, Clevers H.

Development. 2010 Aug;137(16):2653-7. Epub 2010 Jul 7.

Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk.

Bussmann J, Bos FL, Urasaki A, Kawakami K, Duckers HJ, Schulte-Merker S.

Nat Cell Biol. 2011 Jun 26;13(8):944-51. doi: 10.1038/ncb2278.

Variegated gene expression caused by cell-specific long-range DNA interactions.

Noordermeer D, de Wit E, Klous P, van de Werken H, Simonis M, Lopez-Jones M, Eussen B, de Klein A, Singer RH, de Laat W.

EMBO J. 2011 Jul 8;30(16):3298-308. doi: 10.1038/emboj.2011.228.

Tdrd1 acts as a molecular scaffold for Piwi proteins and piRNA targets in zebrafish.

Huang HY, Houwing S, Kaaij LJ, Meppelink A, Redl S, Gauci S, Vos H, Draper BW, Moens CB, Burgering BM, Ladurner P, Krijgsveld J, Berezikov E, Ketting RF.

Leica DM4000 Widefield microscopeLeica DM6000 Fluorescence microscope

Leica AF7000 Fluorescence microscope

Leica MM-AF Fluorescence microscope

Leica SPE confocal microscope

Leica SPE-II confocal microscope

Leica SP5 confocal/multiphoton microscope

Leica SP5 intravital imaging microscope

Leica SP8 confocal microscope

Perkin Elmer Ultraview VoX spinning disk microscope

Zeiss LSM700 confocal microscope

www.hubrecht.eu/information/imagingcenter.html
Acces and/or training upon collaboration with one of the research groups of the Hubrecht Institute
none
No