Molecular Biotechnology


Molecular Biotechnology
jwillemse@chem.leidenuniv.nl
Joost Willemse
Leiden University
Einsteinweg 55
2333 CC
Leiden
Joost Willemse

Gilles van Wezel

Kasia Celler

Live cell imaging,

Fluorescence microscopy

Stereomicroscopy

Live stereomicroscopy

Main interests are the cell division, cytoskeleton, and secretion systems of Strepomycetes species
Willemse, J., J. W. Borst, E. de Waal, T. Bisseling & G. P. van Wezel, (2011a) Positive control of cell division: FtsZ is recruited by SsgB during sporulation of Streptomyces. Genes Dev 25: 89-99.

Willemse, J., A. M. Mommaas & G. P. van Wezel, (2011b) Constitutive expression of ftsZ overrides the whi developmental genes to initiate sporulation of Streptomyces coelicolor. Antonie Van Leeuwenhoek.

Willemse, J. & G. P. van Wezel, (2009) Imaging of Streptomyces coelicolor A3(2) with reduced autofluorescence reveals a novel stage of FtsZ localization. PLoS One 4: e4242.

Noens, E. E., V. Mersinias, J. Willemse, B. A. Traag, E. Laing, K. F. Chater, C. P. Smith, H. K. Koerten & G. P. van Wezel, (2007) Loss of the controlled localization of growth stage-specific cell-wall synthesis pleiotropically affects developmental gene expression in an ssgA mutant of Streptomyces coelicolor. Mol Microbiol 64: 1244-1259.

Xu, Q., B. A. Traag, J. Willemse, D. McMullan, M. D. Miller, M. A. Elsliger, P. Abdubek, T. Astakhova, H. L. Axelrod, C. Bakolitsa, D. Carlton, C. Chen, H. J. Chiu, M. Chruszcz, T. Clayton, D. Das, M. C. Deller, L. Duan, K. Ellrott, D. Ernst, C. L. Farr, J. Feuerhelm, J. C. Grant, A. Grzechnik, S. K. Grzechnik, G. W. Han, L. Jaroszewski, K. K. Jin, H. E. Klock, M. W. Knuth, P. Kozbial, S. S. Krishna, A. Kumar, D. Marciano, W. Minor, A. M. Mommaas, A. T. Morse, E. Nigoghossian, A. Nopakun, L. Okach, S. Oommachen, J. Paulsen, C. Puckett, R. Reyes, C. L. Rife, N. Sefcovic, H. J. Tien, C. B. Trame, H. van den Bedem, S. Wang, D. Weekes, K. O. Hodgson, J. Wooley, A. M. Deacon, A. Godzik, S. A. Lesley, I. A. Wilson & G. P. van Wezel, (2009) Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes. J Biol Chem 284: 25268-25279.

Zeiss Observer, Zeiss fluorescence microscope, Zeiss stereomacroscope with fluorescence, leice stereomacroscope, zeiss light microscope
mbt.lic.leidenuniv.nl
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