RUN MC Dept of Pathology 824


RUN MC Dept of Pathology 824
i.otte@pathol.umcn.nl
I. Otte-Holler
Radboud University Nijmegen
P.O. Box 1901
6500 HB
Nijmegen
run_mc_dept_pathology
H. van KriekenM. Lammens

H. Dijkman

and others

Electronmicroscopy (EM)Energy Dispersive X-ray analyis (EDX)

High Pressure freezing (HPF)

Automated Freeze Substitution (AFS)

Confocal Laser Scanning Microscopy (CLSM)

Laser Microsdissection (LMD)

Image Cytometry

Fluorescent microscopy

High expertise in ultrastructural imaging of f.i. Kidney, Muscle and Nerve tissue for diagnostics and research purposeCancer research in precursors and development.
1. Mild muscular features in tenascin-XB knockout mice, a model of Ehlers-Danlos syndrome. Connect Tissue Res 2011 Mar15. Voermans NC et all2. Simultaneous assessment of DNA ploidy and biomarker expression in paraffin-embedded tissue sections. Histopathology. 2010 Jul;57(1):14-26. Fleskens SJ et all

3. The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology. Am J Pathol. 2010 May;176(5):2188-97. Epub 2010 Mar 26.

4. Morphology of partial globozoospermia. J Androl. 2011 Mar-Apr;32(2):199-206. Epub 2010 Sep 23. Dam AH et all

5. Talcosis due to abundant use of cosmetic talcum powder.Eur Respir Rev. 2010 Jun 1;19(116):165-8. van Huistede A et all

Jeol EM1200, Thermo Tracor EDX, leica CLSM AOBS TCS SP2, Leica LMD, Leica High Content fluorescent microscope, Leica QPath analysis station, Zeiss microscope with KS400 analysis software, Olympus Automated slide scanner.
www.umcn.nl/Research/Departments/Pathology/Pages/default.aspx
personal training en guidance in use of the above mentioned microscopes
none
Yes